traumatic brain injury — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T22323	Enoxaparin sodium		Thrombin
	Enoxaparin sodium is a low-molecular-weight heparin (LMWH) that has recently been approved by the US FDA for use in patients with medically managed ST-segment myocardial infarction (STEMI), or STEMI with subsequent percu...		Thrombin
T1461	Candesartan	CV 11974	RAAS
	Candesartan (CV 11974) is an angiotensin II receptor blocker used widely in the therapy of hypertension and heart failure.		RAAS
T33519	MTOB	α-keto-γ-Methylthiobutyric acid,KMBA,MTOB salt,4-methylthio 2-oxobutyric acid	Others
	MTOB (α-keto-γ-Methylthiobutyric acid) is a substrate for c-terminal binding protein (CtBP) that interferes with the carcinogenic activity of CtBP in cell culture and mice. It also actively regulates TCF-4 signaling, lea...		Others
T36857L	Premarin	Estrone 3-sulfate,Estrone sulfate	Estrogen Receptor/ERR
	Premarin (Estrone 3-sulfate) is an an estrogen sulfate with neuroprotective actions during traumatic brain injury.		Estrogen Receptor/ERR
T33535	MW01-2-151SRM	MW 151,MW-151,MW012151SRM,MW151,MW01 2 151SRM	Others
	MW01-2-151SRM is a novel small molecule inhibitor of microglia activation that crosses the blood-brain barrier, has anti-neuroinflammatory effects, attenuates the up-regulation of glial cytokines in models of neuroinflam...		Others
T60507	Utreloxastat
	Utreloxastat is a compound used to study diseases including alpha-synucleinopathies, tauopathies, ALS, traumatic brain injury, and ischemic-reperfusion related injuries.
T10808	CHPG sodium salt		NF-κB , GluR
	CHPG sodium salt is a selective agonist of mGluR5 and activates the ERK and Akt signaling pathways. CHPG sodium salt can be used in studies about traumatic brain injury.		NF-κB , GluR
T22346	Indomethacin sodium hydrate	Indometacin sodium hydrate	COX
	Indomethacin sodium hydrate (Indometacin sodium hydrate) is an orally active, competitive and reversible COX1/2 inhibitor with potential anti-inflammatory activity in induced migraines, induced gastrointestinal injuries,...		COX
T34249	Rabeximod	ROB-803	TLR
	Rabeximod is a potent immunomodulator that reduces the severity of autoimmune diseases in rat models. Rabeximod inhibits arthritis in a time-dependent manner by stimulating TLR2 and TLR4 downstream to block the activatio...		TLR
T1880	P7C3		Others
	The P7C3 class of neuroprotective aminopropyl carbazoles has been shown to block neuronal cell death in models of neurodegeneration. We now show that P7C3 molecules additionally preserve axonal integrity after injury, be...		Others
T1208	Citicoline sodium	Citicoline sodium salt,CDP-choline	Apoptosis , Others , Endogenous Metabolite
	Citicoline sodium (CDP-choline) is an endogenous intermediate in the synthesis of phosphatidylcholine. It also serves as a choline donor in the biosynthesis of the neurotransmitter acetylcholine. Citicoline sodium demons...		Apoptosis , Others , Endogenous Metabolite
T4956	Tetrahydroxystilbene-2-O-β-D-glucoside	tetrahydroxyl diphenylethylene-2-o-gluco,EH-201	Others
	Tetrahydroxystilbene-2-O-β-D-glucoside (EH-201) is a low MW inducer of erythropoietin. Tetrahydroxystilbene-2-O-β-D-glucoside induces expression of erythropoietin, PPAR-γ coactivator 1α (PGC-1α) and haemoglobin in astroc...		Others
T33765	NVX-108	Dodecafluoropentane,DDFP,Perfluoropentane
	NVX-108 is an exceptional oxygen transporter which increases brain tissue oxygen tension (PbtO2) when administered soon after traumatic brain injury (TBI).
T1158L	Phenoxybenzamine	NSC-37448,A688,NSC 37448,NSC37448,A-688
	Phenoxybenzamine is an α-1 adrenergic receptor antagonist. Phenoxybenzamine may exert a neuroprotective effect by reducing neuroinflammation after traumatic brain injury.
T26627	Anatibant	LF16-0687,LF-16-0687,LF 160687,LF 16-0687,LF-160687
	Anatibant is a potent non-peptide bradykinin B2 receptor antagonist. Anatibant reduces intracranial hypertension and histopathological damage after experimental traumatic brain injury.
T73214	RX 801077	2 BFI free base
	RX 801077 (2 BFI free base), a selective imidazoline I2 receptor (I2R) agonist, exhibits a K i value of 70.1 nM, demonstrating anti-inflammatory and neuroprotective properties. This compound holds research potential for ...
T83963	Z-DEVD-FMK Caspase-3 Inhibitor
	Z-DEVD-FMK, a Caspase-3 Inhibitor, is an irreversible, cell-permeable inhibitor of caspase-3/CPP32 that impedes tumor cell apoptosis. In vivo studies show it offers neuroprotection in rat hippocampi post-seizures and con...
T36903	Rasagiline-13C3 (mesylate)	Rasagiline-13C3 (mesylate)
	Rasagiline-13C3is intended for use as an internal standard for the quantification of rasagiline by GC- or LC-MS. Rasagiline is an inhibitor of monoamine oxidase B (MAO-B; IC50= 4.43 nM for the rat brain enzyme).1It is se...